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Convenient Syntheses of Homopropargylglycine
Citation key 053.2008.dong
Author Dong, S. L. and Merkel, L. and Moroder, L. and Budisa, N.
Pages 1148-1150
Year 2008
DOI 10.1002/psc.1065
Journal J. Peptide Sci.
Volume 14
Number 10
Abstract An improved classic Strecker synthesis was elaborated leading to racemic homopropargylglycine (Hpg) in 61% overall yield, while an asymmetric Strecker reaction produced Hpg and the higher homolog 2-aminohept-6-ynoic acid in significantly higher yields and over 80% ee. Copyright © 2008 European Peptide Society and John Wiley & Sons, Ltd.
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